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    <import namespace="http://fasb.org/us-gaap/2026" schemaLocation="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd" />
    <import namespace="http://fasb.org/us-types/2026" schemaLocation="https://xbrl.fasb.org/us-gaap/2026/elts/us-types-2026.xsd" />
    <import namespace="http://www.xbrl.org/dtr/type/2024-01-31" schemaLocation="https://www.xbrl.org/dtr/type/2024-01-31/types.xsd" />
    <import namespace="http://xbrl.sec.gov/ecd/2026" schemaLocation="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd" />
    <import namespace="http://xbrl.sec.gov/country/2026" schemaLocation="https://xbrl.sec.gov/country/2026/country-2026.xsd" />
    <import namespace="http://fasb.org/srt/2026" schemaLocation="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd" />
    <import namespace="http://fasb.org/srt-types/2026" schemaLocation="https://xbrl.fasb.org/srt/2026/elts/srt-types-2026.xsd" />
    <element id="AKTX_AmericanDepositarySharesEachRepresenting80000OrdinarySharesParValue0.000000005PerShareMember" name="AmericanDepositarySharesEachRepresenting80000OrdinarySharesParValue0.000000005PerShareMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_OrdinaryShares0.000000005ParValuePerShareMember" name="OrdinaryShares0.000000005ParValuePerShareMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_ADSMember" name="ADSMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_GrossCarryingAmountMember" name="GrossCarryingAmountMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AKTX101Member" name="AKTX101Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_CumulativeImpairmentChargeMember" name="CumulativeImpairmentChargeMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_NetBookValueMember" name="NetBookValueMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_PHP303Member" name="PHP303Member" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_SeptemberTwoThousandTwentyFourNotePayableMember" name="SeptemberTwoThousandTwentyFourNotePayableMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AprilTwoThousandTwentyThreeConvertibleNotesMember" name="AprilTwoThousandTwentyThreeConvertibleNotesMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AprilTwoThousandTwentyThreeConvertibleNotesAndWarrantsAmendmentMember" name="AprilTwoThousandTwentyThreeConvertibleNotesAndWarrantsAmendmentMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_LetterAgreementMember" name="LetterAgreementMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AprilTwoThousandTwentyThreePeakBioConvertibleNoteholderWarrantsMember" name="AprilTwoThousandTwentyThreePeakBioConvertibleNoteholderWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AprilTwoThousandTwentyThreeConvertibleNoteMember" name="AprilTwoThousandTwentyThreeConvertibleNoteMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_OrdinarySharesMember" name="OrdinarySharesMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_PreviousAllotmentOptionMember" name="PreviousAllotmentOptionMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AmericanDepositarySharesMember" name="AmericanDepositarySharesMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_ELOCPurchaseAgreementMember" name="ELOCPurchaseAgreementMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_WhiteLionCapitalLLCMember" name="WhiteLionCapitalLLCMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_SeriesGWarrantsMember" name="SeriesGWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_SeriesGWarrantMember" name="SeriesGWarrantMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_TwentyThousandTwentyFiveRegisteredDirectOfferingMember" name="TwentyThousandTwentyFiveRegisteredDirectOfferingMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_TwentyThousandTwentySixRegisteredDirectOfferingMember" name="TwentyThousandTwentySixRegisteredDirectOfferingMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_PrefundedWarrantMember" name="PrefundedWarrantMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_SeriesHWarrantMember" name="SeriesHWarrantMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_SeriesIWarrantMember" name="SeriesIWarrantMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_SeriesJWarrantMember" name="SeriesJWarrantMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_MayTwoThousandTwentySixInvestorPrefundedWarrantMember" name="MayTwoThousandTwentySixInvestorPrefundedWarrantMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_DecemberTwoThousandAndTwentyFiveInvestorPrefundedWarrantMember" name="DecemberTwoThousandAndTwentyFiveInvestorPrefundedWarrantMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_MayTwoThousandTwentySixSeriesHInvestorWarrantsMember" name="MayTwoThousandTwentySixSeriesHInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_MayTwoThousandTwentySixSeriesIInvestorWarrantsMember" name="MayTwoThousandTwentySixSeriesIInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_MayTwoThousandTwentySixSeriesJInvestorWarrantsMember" name="MayTwoThousandTwentySixSeriesJInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AprilTwoThousandTwentyFiveInvestorPrefundedWarrantsMember" name="AprilTwoThousandTwentyFiveInvestorPrefundedWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_OctoberTwoThousandAndTwentyThreeInvestorPrefundedMember" name="OctoberTwoThousandAndTwentyThreeInvestorPrefundedMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_DecemberTwoThousandAndTwentyFiveSeriesGInvestorWarrantsMember" name="DecemberTwoThousandAndTwentyFiveSeriesGInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_DecemberTwoThousandAndTwentyFiveNoteWarrantsMember" name="DecemberTwoThousandAndTwentyFiveNoteWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_DecemberTwoThousandAndTwentyFivePlacementAgentWarrantsMember" name="DecemberTwoThousandAndTwentyFivePlacementAgentWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AprilTwoThousandTwentyThreePeakBioWarrantsMember" name="AprilTwoThousandTwentyThreePeakBioWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_MarchTwoThousandAndTwentyFiveSeriesAInvestorWarrantsMember" name="MarchTwoThousandAndTwentyFiveSeriesAInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_MarchTwoThousandAndTwentyFiveInvestorWarrantsMember" name="MarchTwoThousandAndTwentyFiveInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AprilTwoThousandAndTwentyFiveSeriesAInvestorWarrantsMember" name="AprilTwoThousandAndTwentyFiveSeriesAInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AprilTwoThousandAndTwentyFiveInvestorWarrantsMember" name="AprilTwoThousandAndTwentyFiveInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_OctoberTwoThousandAndTwentyFiveSeriesEInvestorWarrantsMember" name="OctoberTwoThousandAndTwentyFiveSeriesEInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_OctoberTwoThousandAndTwentyFiveSeriesFInvestorWarrantsMember" name="OctoberTwoThousandAndTwentyFiveSeriesFInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_OctoberTwoThousandAndTwentyFivePlacementAgentWarrantsMember" name="OctoberTwoThousandAndTwentyFivePlacementAgentWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_MayTwoThousandAndTwentyFourInvestorWarrantsMember" name="MayTwoThousandAndTwentyFourInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_MarchTwoThousandAndTwentyFourPlacementAgentWarrantsMember" name="MarchTwoThousandAndTwentyFourPlacementAgentWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_MayTwoThousandAndTwentyFourPlacementAgentWarrantsMember" name="MayTwoThousandAndTwentyFourPlacementAgentWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_NovemberTwoThousandAndTwentyFourInvestorWarrantsMember" name="NovemberTwoThousandAndTwentyFourInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_OctoberTwoThousandAndTwentyThreePlacementAgentWarrantsMember" name="OctoberTwoThousandAndTwentyThreePlacementAgentWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_MarchTwoThousandAndTwentyTwoInvestorWarrantsMember" name="MarchTwoThousandAndTwentyTwoInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_MarchTwoThousandAndTwentyTwoPlacementAgentWarrantsMember" name="MarchTwoThousandAndTwentyTwoPlacementAgentWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_DecemberTwoThousandAndTwentyOneInvestorWarrantsMember" name="DecemberTwoThousandAndTwentyOneInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_DecemberTwoThousandAndTwentyOnePlacementAgentWarrantsMember" name="DecemberTwoThousandAndTwentyOnePlacementAgentWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_JulyTwoThousandAndTwentyOnePlacementAgentWarrantsMember" name="JulyTwoThousandAndTwentyOnePlacementAgentWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AprilTwoThousandTwentyThreePeakBioWarrantsOneMember" name="AprilTwoThousandTwentyThreePeakBioWarrantsOneMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_SeptemberTwoThousandTwentyTwoSeriesBInvestorWarrantsMember" name="SeptemberTwoThousandTwentyTwoSeriesBInvestorWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_NovemberTwoThousandTwentyTwoPeakBioWarrantsMember" name="NovemberTwoThousandTwentyTwoPeakBioWarrantsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_EquityIncentivePlan2014EquityIncentivePlan2023AndPeakBio2022LongTermIncentivePlanMember" name="EquityIncentivePlan2014EquityIncentivePlan2023AndPeakBio2022LongTermIncentivePlanMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_UnvestedStockOptionMember" name="UnvestedStockOptionMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_ResearchAndDevelopmentExpensesMember" name="ResearchAndDevelopmentExpensesMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_SellingGeneralAndAdministrativeExpenseMember" name="SellingGeneralAndAdministrativeExpenseMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_SeptemberTwoThousandTwentyTwoSeriesBMember" name="SeptemberTwoThousandTwentyTwoSeriesBMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_TotalWarrantLiabilityMember" name="TotalWarrantLiabilityMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_DerivativeLiabilityMember" name="DerivativeLiabilityMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_ImpairmentLossOnOtherIntangibleAssetsMember" name="ImpairmentLossOnOtherIntangibleAssetsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_ExpectedCurrentYearLossAndHistoricalLossMember" name="ExpectedCurrentYearLossAndHistoricalLossMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_ADCPreClinicalDevelopmentMember" name="ADCPreClinicalDevelopmentMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_SignificantSegmentExpenseCategoryMember" name="SignificantSegmentExpenseCategoryMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_HSCTTMAAK901ProgramMember" name="HSCTTMAAK901ProgramMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_ChemistryManufacturingAndControlMember" name="ChemistryManufacturingAndControlMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_OtherExternalDevelopmentExpenseIncomeMember" name="OtherExternalDevelopmentExpenseIncomeMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_InternalAndOtherResearchAndDevelopmentExpenseMember" name="InternalAndOtherResearchAndDevelopmentExpenseMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_BayerAcquisitionAgreementMember" name="BayerAcquisitionAgreementMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_SettlementAgreementMember" name="SettlementAgreementMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_WarrantAgreementsMember" name="WarrantAgreementsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_WarrantLiabilitiesCurrent" name="WarrantLiabilitiesCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_CapitalRedemptionReserve" name="CapitalRedemptionReserve" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_GainOnSettlementOfCurrentLiabilities" name="GainOnSettlementOfCurrentLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_IssuanceOfShareCapitalForPaymentsInKind" name="IssuanceOfShareCapitalForPaymentsInKind" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AdjustmentsAccretionOfDebtIssuanceCostsOnNotesPayableAndNotesPayableRelatedParty" name="AdjustmentsAccretionOfDebtIssuanceCostsOnNotesPayableAndNotesPayableRelatedParty" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_ProceedsFromIssuanceOfSharesNetOfIssuanceCosts" name="ProceedsFromIssuanceOfSharesNetOfIssuanceCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_FinancingCostsInAccruedExpenses" name="FinancingCostsInAccruedExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_IssuanceOfShareCapitalForSettlementOfConvertibleNotesRelatedParty" name="IssuanceOfShareCapitalForSettlementOfConvertibleNotesRelatedParty" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_IssuanceOfShareCapitalForSettlementOfRelatedPartyDebt" name="IssuanceOfShareCapitalForSettlementOfRelatedPartyDebt" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_IssuanceOfShareCapitalForPaymentInKind" name="IssuanceOfShareCapitalForPaymentInKind" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_ShorttermFinancingArrangement" name="ShorttermFinancingArrangement" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_Rule10b51ArrModifiedFlag" name="Rule10b51ArrModifiedFlag" nillable="true" xbrli:periodType="duration" type="xbrli:booleanItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_NonRule10b51ArrModifiedFlag" name="NonRule10b51ArrModifiedFlag" nillable="true" xbrli:periodType="duration" type="xbrli:booleanItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_ScheduleOfWarrantsActivityTextBlock" name="ScheduleOfWarrantsActivityTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_DisclosureOfFairValueAssumptionsOfWarrantsTableTextBlock" name="DisclosureOfFairValueAssumptionsOfWarrantsTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_IssuanceOfShareCapitalUponConversionOfDeferredShares" name="IssuanceOfShareCapitalUponConversionOfDeferredShares" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AccruedExternalResearchAndDevelopmentExpenses" name="AccruedExternalResearchAndDevelopmentExpenses" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_ClassOfWarrantOrRightOutstandingEquity" name="ClassOfWarrantOrRightOutstandingEquity" nillable="true" xbrli:periodType="instant" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_ClassOfWarrantOrRightOutstandingLiability" name="ClassOfWarrantOrRightOutstandingLiability" nillable="true" xbrli:periodType="instant" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_LiabilityclassifiedWarrants" name="LiabilityclassifiedWarrants" nillable="true" xbrli:periodType="instant" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_WeightedAverageExercisePriceOutstandingWarrants" name="WeightedAverageExercisePriceOutstandingWarrants" nillable="true" xbrli:periodType="instant" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_WeightedAverageExercisePriceIssuedWarrants" name="WeightedAverageExercisePriceIssuedWarrants" nillable="true" xbrli:periodType="duration" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_WeightedAverageExercisePriceExercisedWarrants" name="WeightedAverageExercisePriceExercisedWarrants" nillable="true" xbrli:periodType="duration" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_WeightedAverageExercisePriceExpiredWarrants" name="WeightedAverageExercisePriceExpiredWarrants" nillable="true" xbrli:periodType="duration" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_NumberOfOrdinarySharesRepresentingOneAmericanDepositaryShare" name="NumberOfOrdinarySharesRepresentingOneAmericanDepositaryShare" nillable="true" xbrli:periodType="instant" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_TradingPricePercentage" name="TradingPricePercentage" nillable="true" xbrli:periodType="instant" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_TradingPriceDiscountPercentage" name="TradingPriceDiscountPercentage" nillable="true" xbrli:periodType="instant" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_VolumeWeightedAveragePrice" name="VolumeWeightedAveragePrice" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_TradingPercentageThereafter" name="TradingPercentageThereafter" nillable="true" xbrli:periodType="instant" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_BeneficialOwnershipLimitationPercentage" name="BeneficialOwnershipLimitationPercentage" nillable="true" xbrli:periodType="instant" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_BeneficialOwnershipLimitationPercentageIncrease" name="BeneficialOwnershipLimitationPercentageIncrease" nillable="true" xbrli:periodType="instant" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_SubscriptionAmount" name="SubscriptionAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_CompensationRelatedCostsSharebasedPaymentsAbstract" name="CompensationRelatedCostsSharebasedPaymentsAbstract" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable" name="EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" />
    <element id="AKTX_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsUnderlyingVestedInPeriod" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsUnderlyingVestedInPeriod" nillable="true" xbrli:periodType="instant" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_GrossProceedsFromFinancing" name="GrossProceedsFromFinancing" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityExtinguishmentOfLiability" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityExtinguishmentOfLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_AmountDueToRelatedParty" name="AmountDueToRelatedParty" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_QualifiedFinancing" name="QualifiedFinancing" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="AKTX_PurchaseAgreementMember" name="PurchaseAgreementMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
</schema>
